Method for selective diversification of a cis-acting diversification activator and the nucleic acid

摘要

The present invention is a necessary and sufficient for the activation of diversification in transcription units linked to itself, relating to the identification of cis-acting diversification activator (DIVAC). The present invention relates to a genetic construct comprising a diversification activator, comprising introducing into a recipient cell, provides a method for diversification of a target nucleic acid, wherein the diversification activator is a target nucleic acid It has been linked. The present invention relates to a genetic construct comprising a diversification activator of the invention, can be introduced into a recipient cell, comprising producing a recombinant recipient cell, provides a method for diversification of a target nucleic acid, Here in the diversification activator is linked to the target nucleic acid.