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Post-traumatic stress disorder, treatment of obsessive-compulsive disorder and related neuropsychiatric disorders

机译:创伤后应激障碍,强迫症和相关神经精神病的治疗

摘要

(57) [summary] The present invention describes a new treatment of neuropsychiatric disorders. This failure, nerve schizophrenic symptoms anxiety disorders, mood disorders, psychotic disorders, somatoform disorders, and results from the movement disorders. Treatment of the present invention utilize any agent that acts at the same time as the GABA-A receptor agonist and NMDA glutamate receptor antagonist. These two activities are characteristic of the single agents, for example, pro Akamu insert preferably is (N- acetylhomopiperazine Tauri calcium sulfonates). Alternatively, to obtain combined as a compound or mixture, the separate agents with these activities, and may be administered together thereby. Further, the present invention, there is provided a third agent that acts as an ion channel blocker or noncompetitive NMDA receptor blocking agent. This enhances the effect of the major treatment. Preferred ion channel blockers particular is magnesium.
机译:(57)[概述]本发明描述了神经精神疾病的新治疗方法。这种衰竭,神经精神分裂症症状,焦虑症,情绪障碍,精神病,躯体形式障碍,以及运动障碍导致。本发明的治疗利用与GABA-A受体激动剂和NMDA谷氨酸受体拮抗剂同时起作用的任何试剂。这两种活性是单一药剂的特征,例如,Akamu插入物优选是(N-乙酰基高哌嗪Tauri磺酸钙)。或者,为了获得作为化合物或混合物的组合,具有这些活性的分离剂可以由此一起给药。此外,本发明提供了充当离子通道阻滞剂或非竞争性NMDA受体阻滞剂的第三剂。这增强了主要治疗的效果。优选的离子通道阻滞剂特别是镁。

著录项

  • 公开/公告号JP4633262B2

    专利类型

  • 公开/公告日2011-02-16

    原文格式PDF

  • 申请/专利权人 シンクロニュ-ロン;エルエルシ-;

    申请/专利号JP2000606206

  • 发明设计人 フォゲル;バリー エス.;

    申请日2000-03-17

  • 分类号A61K31/255;A61K9/08;A61K9/10;A61K9/20;A61K9/52;A61K9/70;A61P25/22;A61P25/24;

  • 国家 JP

  • 入库时间 2022-08-21 18:20:02

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