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Novel potassium channel and gene encoding the same potassium channel

机译:新型钾通道和编码相同钾通道的基因

摘要

This invention relates to novel potassium channels and genes encoding these channels. More specifically the invention provides isolated polynucleotides encoding the KCNQ4 potassium channel, cells transformed with these polynucleotides, transgenic animals comprising genetic mutations, and the use of the transformed cells and the transgenic animals for the in vitro and in vivo screening of drugs affecting KCNQ4 containing potassium channels.
机译:本发明涉及新的钾通道和编码这些通道的基因。更具体地,本发明提供了编码KCNQ4钾通道的分离的多核苷酸,用这些多核苷酸转化的细胞,包含遗传突变的转基因动物,以及转化的细胞和转基因动物在体外和体内筛选影响含KCNQ4的钾的药物中的用途。渠道。

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