The refolding medicine of the protein and it is refolding

摘要

PROBLEM TO BE SOLVED: To provide a refolding agent which can produce a highly pure protein with good productivity, and a refolding method.;SOLUTION: The refolding agent comprises a phosphorus-containing compound (A). The refolding method comprises a step of treating an unfolded protein with the refolding agent, and the concentration of the compound (A) in the step is 0.2-6 mol/L.;COPYRIGHT: (C)2007,JPO&INPIT