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TREATMENT OF RESISTANT OR REFRACTORY CANCERS WITH MULTI-ARM POLYMERIC CONJUGATES OF 7-ETHYL-10-HYDROXYCAMPTOTHECIN

机译：7-乙基-10-羟基喜树碱多臂聚合物缀合物处理抗性或耐药性癌症

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摘要

A method of treating a resistant or refractory cancer in a mammal includes administering an effective amount of a compound of; embedded image

;to the mammal. In preferred aspects, the cancer is resistant or refractory to CPT-11 or CPT therapy.

机译：在哺乳动物中治疗抗药性或难治性癌症的方法包括给予有效量的下列化合物： “嵌入式图像”

对哺乳动物。在优选的方面，所述癌症对CPT-11或CPT疗法有抗性或难治性。