首页>
外国专利>
ENZYME ACTIVITY ASSAY USING ROLLING CIRCLE AMPLIFICATION
ENZYME ACTIVITY ASSAY USING ROLLING CIRCLE AMPLIFICATION
展开▼
机译:使用滚环放大率进行酶活性评估
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention relates to an enzyme activity assay using rolling circle amplification for verifying that a sample contains the enzyme activity in question. Thus, the present invention pertains to a method for determining the presence or absence of one or more enzyme activities involved in circularising a non-circular oligonucleotide probe in a biological sample. Furthermore, the present invention concerns liquid compositions comprising one or more oligonucleotide probes. Within the scope of the present invention is also a composition comprising a liquid composition and a tissue sample, and solid support of one or more oligonucleotides of the present invention. Disclosed is also a microfluidic device with one or more compartments for performing rolling circle amplification events, and a method for correlating one or more rolling circle amplification events. Methods for testing the efficacy of a drug, for diagnosing or prognosing a disease, for treating a disease, or for treating prophylactically a disease is furthermore disclosed.
展开▼