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Antiviral Oligonucleotides Having a Conserved G4 Core Sequence

机译：具有保守的G4核心序列的抗病毒寡核苷酸

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摘要

Modified oligonucleotides having a conserved G₄sequence and a sufficient number of flanking nucleotides to significantly inhibit the activity of a virus are provided. G₄quartet oligonucleotide structures are also provided. Methods of prophylaxis, diagnostics and therapeutics for viral-associated diseases are also provided.

机译：提供了具有保守的G _{4 序列和足够数量的侧翼核苷酸以显着抑制病毒活性的修饰寡核苷酸。还提供了G _{4 四重奏寡核苷酸结构。还提供了病毒相关疾病的预防，诊断和治疗方法。}}

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公开/公告号US2011124715A1

专利类型
公开/公告日2011-05-26

原文格式PDF
申请/专利权人 RONNIE C. HANECAK;KEVIN P. ANDERSON;C. FRANK BENNETT;MING-YI CHIANG;VICKIE L. BROWN-DRIVER;DAVID J. ECKER;TIMOTHY VICKERS;JACQUELINE R. WYATT;
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申请/专利号US20100849886
发明设计人 RONNIE C. HANECAK;KEVIN P. ANDERSON;C. FRANK BENNETT;MING-YI CHIANG;VICKIE L. BROWN-DRIVER;DAVID J. ECKER;TIMOTHY VICKERS;JACQUELINE R. WYATT;
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申请日2010-08-04
分类号A61K31/7088;C12N7;A61P31/16;A61P31/18;A61P31/22;
国家 US
入库时间 2022-08-21 18:14:39

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