Antiviral macrocycle derivatives and metal complexes, incorporating bridged macrocycles

摘要

A compound of Formulae (1), (2) or (3), A₁-Ph (1) or A₁-Ar-A₂ (2) or A₁-(A₂)A′-A₃ (3) wherein A₁, A₂ and A₃ are selected from Formulae 4, 5 and 6:; or a salt whereof; wherein Ar is selected from the group consisting of 1,2-phenyl, 1,3-phenyl and 1,4-phenyl optionally substituted with one or more methyl groups; m and n are independently integers from 0 to 1; Ph is phenyl, optionally substituted with one or more methyl groups; Ar¹ is trisubstituted phenyl optionally substituted with one or more phenyl groups; and R¹, R² and R³ are independently selected from the group consisting of H, Me and linear chain C₂-C₄ alkyl.