CATALYST FOR CROSS-COUPLING REACTION, AND PROCESS FOR PRODUCTION OF AROMATIC COMPOUND USING THE SAME

摘要

The present invention provides a process for efficiently producing an alkylated aromatic compound in good yield, by a cross-coupling reaction between an alkyl halide and an aromatic magnesium reagent. A process for producing an aromatic compound represented by Formula (1):; R—Ar′  (1)wherein R is a hydrocarbon group, and Ar′ is an aryl group;the process comprising:reacting a compound represented by Formula (2):; R—X  (2)wherein X is a halogen atom, and R is as defined above, with a magnesium reagent represented by Formula (3):; Ar′—MgY  (3)wherein Y is a halogen atom, and Ar′ is as defined above, in the presence of a catalyst for cross-coupling reactions comprising an iron compound and a bisphosphine compound represented by Formula (4):; wherein Q is a divalent group derived from an aromatic ring by removing two hydrogen (H) atoms on adjacent carbon atoms; and each Ar is independently an aryl group.