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TREATMENT OF NEONATE FOALS WITH MELOXICAM

机译:美洛昔康处理新生儿小马驹

摘要

A method of administering meloxicam containing compositions to neonate foals of 6 weeks of age or less is provided. The inventors have discovered that foals of 6 weeks of age or less can have meloxicam administered at a dosage of 0.6 mg/kg without any negative or adverse reaction by the foal. The method also provides a dosing regimen for obtaining first peak plasma concentrations of approximately 800 ng/ml, average plasma concentration levels of 200 ng/ml for 6 hours after a single dose, and sustained plasma concentration levels of 100 ng/ml with twice daily dosing.
机译:提供了一种将含美洛昔康的组合物给予6周龄或更小的新生马驹的方法。发明人发现6周龄或更小的小马驹可以以0.6mg / kg的剂量施用美洛昔康,而小马驹没有任何负面或不良反应。该方法还提供了一种给药方案,可在一次给药后的6小时内获得约800 ng / ml的第一峰值血浆浓度,200 ng / ml的平均血浆浓度水平以及每天两次的持续血浆浓度水平为100 ng / ml加药。

著录项

  • 公开/公告号US2011212948A1

    专利类型

  • 公开/公告日2011-09-01

    原文格式PDF

  • 申请/专利权人 GIUSEPPE PIPPIA;SHARANNE RAIDAL;

    申请/专利号US200913062372

  • 发明设计人 GIUSEPPE PIPPIA;SHARANNE RAIDAL;

    申请日2009-07-10

  • 分类号A61K31/5415;C07D417/12;

  • 国家 US

  • 入库时间 2022-08-21 18:13:34

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