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Treatment of neonate foals with meloxicam

机译:美洛昔康治疗新生儿小马驹

摘要

A method of administering meloxicam containing compositions to neonate foals of 6 weeks of age or less is provided. The inventors have discovered that foals of 6 weeks of age or less can have meloxicam administered at a dosage of 0.6 mg/kg without any negative or adverse reaction by the foal. The method also provides a dosing regimen for obtaining first peak plasma concentrations of approximately 800ng/ml, average plasma concentration levels of 200ng/ml for 6 hours after a single dose, and sustained plasma concentration levels of 100ng/ml with twice daily dosing.
机译:提供了一种将含美洛昔康的组合物给予6周龄或更小的新生马驹的方法。发明人发现6周龄或更小的小马驹可以以0.6mg / kg的剂量施用美洛昔康,而小马驹没有任何负面或不良反应。该方法还提供了给药方案,用于在单次给药后6小时获得大约800ng / ml的第一峰值血浆浓度,200ng / ml的平均血浆浓度水平以及每天两次给药的持续血浆浓度水平100ng / ml。

著录项

  • 公开/公告号AU2009290119B2

    专利类型

  • 公开/公告日2015-08-20

    原文格式PDF

  • 申请/专利权人 TROY LABORATORIES PTY LIMITED;

    申请/专利号AU20090290119

  • 发明设计人 PIPPIA GIUSEPPE;RAIDAL SHARANNE;

    申请日2009-07-10

  • 分类号A61K31/5415;A61P29;

  • 国家 AU

  • 入库时间 2022-08-21 15:10:51

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