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METHOD FOR DETERMINING THE STAGE OF ULCERATIVE COLITIS OR INTERSTITIAL PNEUMONITIS AND REAGENT KIT THEREOF

机译:确定溃疡性结肠炎或间质性肺炎的阶段及其试剂盒的方法

摘要

The invention provides a method capable of readily discriminating pathologic conditions and judging selection of a therapeutic drug, the degree of the therapeutic effect, discontinuation of medication, etc., wherein stages quantitatively judged by digitizing substances contained in urine, which is different from conventional methods for judging stages of an ulcerative colitis and an interstitial pneumonitis which are performed by observation of mucous lesions with endoscopy requiring the skill or by analysis of histological samples collected from the living body.;The method measures the value of main metabolites of prostaglandin E (PGE-MUM) concentration in urine and judges stages between the pre-remission phase of and the remission phase of ulcerative colitis.;The method also measures the value of the PGE-MUM concentration in urine and judges stages between the active phase and the non-active phase of interstitial pneumonitis.
机译:本发明提供了一种能够容易地区分病理状况并判断治疗药物的选择,治疗效果的程度,药物的中止等的方法,其中通过对尿中所含物质进行数字化来定量地判断阶段,这与常规方法不同。用于判断溃疡性结肠炎和间质性肺炎的阶段,这些阶段是通过需要技巧的内窥镜观察粘膜病变或通过分析从活体收集的组织学样本来进行的;该方法测量前列腺素E(PGE)的主要代谢物的价值-MUM)浓度并判断溃疡性结肠炎的缓解前阶段与缓解期之间的阶段;该方法还测量尿液中PGE-MUM浓度的值并判断活动期与非尿道炎之间的阶段间质性肺炎活跃期。

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