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METHODS OF DETECTING NUCLEIC ACID WITH MICROARRAY AND PROGRAM PRODUCT FOR USE IN MICROARRAY DATA ANALYSIS

机译:用微阵列和程序产品检测核酸的方法,用于微阵列数据分析

摘要

The invention provides a method of detecting, with a microarray, a target nucleic acid containing a base sequence to which a nucleic acid-binding protein binds, obtaining a signal from a correction probe not containing any sequence complementary to the base sequence to which the nucleic acid-binding protein binds for being used as a background to correct a signal obtained from a detection probe hybridizing to the target nucleic acid, as well as a computer program product for enabling a computer to detect, with a microarray, a target nucleic acid containing a base sequence to which a nucleic acid-binding protein binds.
机译:本发明提供了一种通过微阵列检测包含核酸结合蛋白所结合的碱基序列的靶核酸,从不包含与该核酸所结合的碱基序列互补的序列的校正探针获得信号的方法。酸结合蛋白结合用作背景,以校正从与目标核酸杂交的检测探针获得的信号,以及使计算机能够通过微阵列检测含有以下成分的目标核酸的计算机程序产品核酸结合蛋白结合的碱基序列。

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