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Hansenula polymorpha gene coding for α 1,6-mannosyltransferase and process for the production of recombinant glycoproteins with Hansenula polymorpha mutant strain deficient in the same gene
Hansenula polymorpha gene coding for α 1,6-mannosyltransferase and process for the production of recombinant glycoproteins with Hansenula polymorpha mutant strain deficient in the same gene
Disclosed are a novel Hansenula polymorpha gene coding for α-1,6-mannosyltransferase initiating outer chain elongation, an H. polymorpha mutant strain having a deficiency in the gene, and a process for producing a recombinant glycoprotein using such a mutant strain.
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