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Method of isolating and proliferating autologous antigen-specific CD8+ T cell using anti-4-1BB antibodies
Method of isolating and proliferating autologous antigen-specific CD8+ T cell using anti-4-1BB antibodies
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机译:用抗4-1BB抗体分离和增殖自体抗原特异性CD8 + Sup> T细胞的方法
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摘要
Provided are methods of isolating and proliferating antigen-specific CD8+ T cells using anti-4-1BB antibodies. The methods of isolating and proliferating CD8+ T cells may yield cells at a higher recovery rate than a conventional isolation method, and the isolation method using humanized anti-4-1BB antibodies may also yield cells at a high recovery rate. Further, in cell culture, cells may be grown at a high proliferation rate. The antigen-specific CD8+ T cells yielded according to the isolation and proliferation methods may be used to treat cancer without any side-effects.
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