methods of detecting or diagnosing a neurodegenerative disease or condition in an individual, monitoring the development or progress of a neurodegenerative disease or condition in an individual, and diagnosing a neurodegenerative disease or condition in an individual

摘要

METHODS OF DETECTION OR DIAGNOSIS OF A NEURODEGENERATIVE DISEASE OR CONDITION IN AN INDIVIDUAL, MONITORING THE DEVELOPMENT OR PROGRESS OF A NEURODEGENERATIVE DISEASE AND NEURODEGENERATIVE DISEASE a cerebral spinal fluid sample and testing the sample for the presence of at least one anti-phospholipid autoantibody or nitrosylated antibodies in the sample, the high level of which correlates with a neurodegenerative disease or condition. Alternatively, testing a first sample to determine the level of at least one autoantibody having selected specificity, treating a second sample with an oxidizing agent, testing the second oxidized sample to determine the level of at least one autoantibody having specificity. selected, and compare the level of at least one autoantibody of the first sample with that of the second oxidized sample; The absence of an increase in the level of at least one autoantibody of the second oxidized sample compared to that of the first sample correlates with a neurodegenerative disease or condition.