首页> 外国专利> compound, pharmaceutical composition, compound use, method for elevating hdl in an individual, method for treating type 2 diabetes, decreased insulin resistance or lowering blood pressure in an individual, method for decreasing ldlc in an individual , method for displacing small dense ldl particle size to normal ldl in an individual, method for treating atherosclerotic diseases including vascular disease, coronary heart disease, cerebrovascular disease and peripheral vessel disease in an individual, method for treatment of inflammatory diseases, including rheumatoid arthritis, asthma, osteoarthritis and autoimmune disease in an individual, method of treating a disease or condition as measured by hppar-delta, method of modulating a peroxisome proliferator-activated receptor function ( ppar), and method of treating a disease or condition

compound, pharmaceutical composition, compound use, method for elevating hdl in an individual, method for treating type 2 diabetes, decreased insulin resistance or lowering blood pressure in an individual, method for decreasing ldlc in an individual , method for displacing small dense ldl particle size to normal ldl in an individual, method for treating atherosclerotic diseases including vascular disease, coronary heart disease, cerebrovascular disease and peripheral vessel disease in an individual, method for treatment of inflammatory diseases, including rheumatoid arthritis, asthma, osteoarthritis and autoimmune disease in an individual, method of treating a disease or condition as measured by hppar-delta, method of modulating a peroxisome proliferator-activated receptor function ( ppar), and method of treating a disease or condition

机译:化合物,药物组合物,化合物用途,提高个体hdl的方法,治疗2型糖尿病的方法,降低个体胰岛​​素抵抗或降低血压的方法,降低个体ldlc的方法,置换小的致密ldl粒径的方法对于个体的正常ldl而言,用于治疗个体的动脉粥样硬化性疾病,包括血管疾病,冠心病,脑血管疾病和外周血管疾病的方法,用于治疗个体的炎性疾病,包括类风湿性关节炎,哮喘,骨关节炎和自身免疫性疾病的方法,通过hppar-delta测量的疾病或病症的治疗方法,调节过氧化物酶体增殖物激活的受体功能(ppar)的方法以及疾病或病症的治疗方法

摘要

COMPOUND, PHARMACEUTICAL COMPOSITION, USE OF COMPOUND, METHOD FOR Raising HDL IN AN INDIVIDUAL, METHOD FOR TREATING TYPE 2 DIABETES, RESISTANCE TO REDUCED INSULIN OR REDUCTION OF SINDU INDIVIDUM IN BLOOD PRESSURE . METHOD FOR DISPLACING SMALL DENSIUM LDL PARTICULAR SIZE TO NORMAL LDL IN AN INDIVIDUAL, METHOD FOR TREATMENT OF AEROSCLEROTY DISEASES, VASCULAR CORONARY DISEASE, CORONARY VENTAL DISEASE, METHOD OF INFLAMMATORY DISEASES, INCLUDING RHEUMATIOUS ARTHRITIS, ASTHMA, OSTEODYCHROPHY AND AUTOIMMUNE DISEASE IN AN INDIVIDUAL, METHOD OF TREATMENT OF A DISEASE OR CONDITION MEASURED BY HPPAR-DELTA PERIPLATOR MODULATOR METHOD ), AND METHOD OF TREATING A DISEASE OR CONDITION These are aryl sulfonamide and sulfonyl compounds of formula (I) as peroxisome proliferator-activated receptor modulators, pharmaceutical compositions comprising the same and methods of treating disease which use them.
机译:化合物,药物成分,化合物的使用,个体HDL升高的方法,2型糖尿病的治疗方法,对胰岛素的抵抗力或血压降低的SINDU INDIVIDUM抵抗力。个体将小密度低密度脂蛋白(LDL)大小改变为正常低密度脂蛋白(LDL)的方法,治疗动脉粥样硬化疾病,血管性冠状动脉疾病,冠状动脉性静脉疾病,发炎性疾病,包括风湿性关节炎,关节囊炎,动脉炎,哮喘通过HPPAR-Δ介导剂调节剂方法测定的疾病或病症的治疗方法和治疗方法或疾病这些是过氧化物酶体增殖物活化的受体调节剂的式(I)的芳基磺酰胺和磺酰基化合物,包含其的药物组合物以及使用它们的疾病治疗方法。

著录项

  • 公开/公告号BRPI0508791A

    专利类型

  • 公开/公告日2007-09-04

    原文格式PDF

  • 申请/专利权人 KALYPSYS INC;

    申请/专利号BR2005PI08791

  • 申请日2005-04-07

  • 分类号C07D211/96;A61K31/407;A61K31/445;A61K31/451;A61K31/454;A61K31/4545;A61K31/495;A61K31/496;A61K31/497;A61K31/501;A61K31/504;A61K31/506;A61K31/529;A61K31/551;C07D213/74;C07D237/20;C07D239/42;C07D241/04;C07D241/20;C07D263/58;C07D277/82;C07D295/26;C07D307/46;C07D307/79;C07D317/66;C07D401/04;C07D417/02;C07D417/04;C07D487/08;

  • 国家 BR

  • 入库时间 2022-08-21 20:59:22

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