compound and use thereof, anticancer agent, combined preparation for simultaneous, separate or sequential administration in the treatment of cancer, pharmaceutical composition, radiation sensitizer and sensitizer for an anticancer agent

摘要

B COMPOSITE AND USE OF THE SAME, ANTICHANGEOUS AGENT, COMBINED PREPARATION FOR SIMULTANEOUS, SEPARATE, OR SEQUENTIAL ADMINISTRATION IN CANCER, PHARMACEUTICAL COMPOSITION, RADIATION SENSITIZER A GENERAL SENSITIVE formula (I): wherein A1 is selected from the following formula (aa1); R4 is a lower alkenyl group or lower alkynyl group; R2 is a phenyl, pyridyl or thienyl group; R 5 and R 6 are a hydrogen atom, a lower alkenyl group, or a lower alkyl hydroxy group, etc. The compounds of the invention have excellent weel kinase inhibitory effect and are therefore useful in the medical field, especially in the treatment of various cancers.