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nicotine derivative, nicotine derivative precursor, hapten-carrier conjugate, use of a hapten-carrier conjugate, and vaccine composition

机译：尼古丁衍生物，尼古丁衍生物前体，半抗原-载体缀合物，半抗原-载体缀合物的用途和疫苗组合物

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摘要

B NICOTIN DERIVATIVE, NICOTIN DERIVATIVE PRECURSOR, HAPPENE-CARRIER CONJUGATE, USE OF A HAPPENE-CARRIER CONJUGATE, AND, VACCINE COMPOSITION D The present invention provides a hapten in the form of a new nicotine derivative which can be properly conjugated with an appropriate carrier to produce an effective vaccine against nicotine addiction. More particularly, the invention relates to a nicotine derivative of the following formula (1): The present invention also relates to a hapten-carrier conjugate derived from the aforementioned nicotine derivative and a vaccine composition comprising said hapten conjugate - carrier.

机译：烟碱衍生物，烟碱衍生物前体，H载体缀合物，USE载体缀合物的使用和疫苗组合物本发明提供了新烟碱衍生物形式的半抗原，其可以与之适当地缀合。产生有效的尼古丁成瘾疫苗的合适载体。更具体地，本发明涉及下式（1）的烟碱衍生物：本发明还涉及衍生自上述烟碱衍生物的半抗原-载体缀合物和包含所述半抗原-载体的疫苗组合物。 展开▼

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公开/公告号BRPI0710263A2

专利类型

公开/公告日2011-08-09

原文格式PDF

申请/专利权人 DE STAAT DER NEDERLANDEN VERT. DOOR DE MINISTER VAN VWS;
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申请/专利号BR2007PI10263

发明设计人 PETER HOOGERHOUT;GIJSBERT ZOMER;
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申请日2007-04-20

分类号C07D401/04;A61K31/465;A61K39/385;

国家 BR

入库时间 2022-08-21 18:07:04

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