Composition comprising receptor agonist but of angiotensin (1 - 7) and its use for the modulation of the inflammatory response and / or analgesic

摘要

Composition comprising receptor agonist but of angiotensin (1 - 7) and its use for the modulation of the inflammatory response and / or analgesic. The present invention provides the use of agonists of the receptor and angiotensin (1 - 7), as an alternative pharmacological therapy in the context of inflammatory diseases, such as rheumatoid arthritis.The invention provides compositions comprising angiotensin (1 - 7), its analogues peptidicos or peptide, or a salt, solvato and / or pharmacologically acceptable hydrate and its use in preparation of medicines for the modulation of the inflammatory response and / or analgesic.Among others, the anti-inflammatory effects of the agonists of the receptor and angiotensin (1 - 7), in particular of the bird 0991, inhibit important parameters of the inflammatory response in the model of arthritis induced by MBSA. The present invention provides a new approach of constituents of SARS, the axis eca2 / ang (1 7) / but, associated with specific events of the cascade of the inflammatory response.