Biomaterial of chitosan and hydroxyapatite (cnhap) for bone fill and process for production of the same

摘要

Biomaterial of chitosan and hydroxyapatite (cnhap) for bone fill and process for production of the same process for obtaining the scaffold of a biomaterial hydrogel composite (cnhap) based on chitosan (CN) and hydroxyapatite (HA), with great potential for application in the medical field - Dental care, demonstrating the characteristics of biocompatibility tests evidenced by classical in vitro.These characteristics are associated with the combination of propriedadesfu00edsico chemical and biological materials that compose it. Cnhap was obtained in the form of hydrogel with good mechanical properties, easy handling and modeling, with high porosity, which makes it a promising as materia L of bone fill.The production of scaffold cnhap hydrogel composite was efetuadapor a procedure of mineralization u00ed n situ hydrogel polymeric of LUS per ha. This method of mineralization in situ promoted the mechanical characteristics and bioactivity of the cnhap, suitable for application in medical services.In addition to the biocompatibility, materials for filling tissue should be able to promote adhesion, proliferation, and cell differentiation, essential requirements for bioengineered tissues, which is being increasingly exploited in clinical practice.