首页>
外国专利>
Chromosomal analysis by molecular karyotype assay
Chromosomal analysis by molecular karyotype assay
展开▼
机译:通过分子核型分析进行染色体分析
展开▼
页面导航
摘要
著录项
相似文献
摘要
The invention provides a method of karyotyping (for example for the detection of trisomy) a target cell to detect chromosomal imbalance therein, the method comprising: (a) interrogating closely adjacent biallelic SNPs across the chromosome of the target cell (b) comparing the result at (a) with the SNP haplotype of paternal and maternal chromosomes to assemble a notional haplotype of target cell chromosomes of paternal origin and of maternal origin (c) assessing the notional SNP haplotype of target cell chromosomes of paternal origin and of maternal origin to detect aneuploidy of the chromosome in the target cell. Also provided are related computer-implemented embodiments and systems.
展开▼