method of predicting the effectiveness of treatment of the patients with psoriasis u0438u043du0444u043bu0438u043au0441u0438u043cu0430u0431u043eu043c

摘要

the invention belongs to the field of medicine.namely, dermatology and is a way to predict the effectiveness of treatment of patients with psoriasis by determining the molecular u0438u043du0444u043bu0438u043au0441u0438u043cu0430u0431u043eu043c sta skin biopsy specimens and serum shelter avaand psoriasis patients before starting treatment, production and research u0431u0438u043eu043fu0442u0430u0442u0430 skin and blood serum of psoriasis patients.the definition in the u0431u0438u043eu043fu0442u0430u0442u0435 skin polymorphism in position during the sixth u044du043au0437u043eu043du0430 gene TNF - r - ii, determine the content of il - 10 in serum.in order to u0433u043eu043cu043eu0437u0438u0433u043eu0442u043du043eu0433u043e genotyping tt in position during the sixth u044du043au0437u043eu043du0430 gene TNF - r - ii and high ( 2.7 ng / ml), the content of il - 10 in serum predict the effectiveness of le of,and in identifying the u0433u043eu043cu043eu0437u0438u0433u043eu0442u043du043eu0433u043e genotyping gg position 676 sixth u044du043au0437u043eu043du0430 gene TNF - r - ii and low ( 1.0 pg / ml), the content of il - 10 in serum predict low efficiency u043bu0435u0447u0435u043d whoa.this method saves considerable material resources spent on treatment, but also avoid the side effects of therapy.