USE OF RECOMBINANT ACTIVATED PROTEIN C IN THE MANUFACTURE OF MEDICAMENTS FOR TREATING OR PREVENTING ACQUIRED HYPERCOAGULABLE STATES ASSOCIATED WITH SEPSIS

摘要

A method of treatment for human patients with an acquired hypercoagulable state or acquired protein C deficiency associated with sepsis, purpura fulminans, meningococcal sepsis, bone marrow and other transplantations, severe burns, pregnancy, major surgery, severe trauma, or ARDS, which comprises administering activated protein C providing a highly selective therapeutic agent with a low potential for causing bleeding complications.