METHOD FOR IDENTIFICATION OF A CHEMICAL COMPOUND WHICH MODULATES THE ACTIVITY OF A MAMMALIAN GLYCOSYL-PHOSPHATIDYL-INOSITOL SPECIFIC PHOSPHOLIPASE C

摘要

The present invention refers to a method for identification of a chemical compound which modulates the activity of mammalian GPI-PLC wherein aÜ a mammalian cell is incubated with glimepiride; bÜ hcDIGs of the cells of aÜ are prepared; cÜ the hcDIGs from bÜ are incubated with a chemical compound; dÜ the activity of the GPI-PLC from the hcDIGs of cÜ is determined. IMAGE