COMBINATION OF THE CORE AND OTHER ANTIGENS OF HEPATITIS C VIRUS (HCV) AND USE THEREOF IN IMMUNOASSAYS FOR ANTI-HCV ANTIBODIES

摘要

Combinations of HCV antigens that have a broader range of immunological reactivity than any single HCV antigen. The combinations consist of an antigen from the C domain of the HCV polyprotein, and at least one additional HCV antigen from either the NS3 domain, the NS4 domain, the S domain, or the NS5 domain, and are in the form of a fusion protein, a simple physical mixture, or the individual antigens commonly bound to a solid matrix.