COMPOSITIONS COMPRISING AN OIL, A POLYSACCHARIDE IN INTIMATE ASSOCIATION WITH SILICA NANOPARTICLES AND A PROTEIN OR PEPTIDE NON-COVALENTLY ASSOCIATED WITH SAID NANOPARTICLES AND POLYSACCHARIDE

摘要

Disclosed is a pharmaceutical composition for oral use, comprising an oil having particulate matter suspended therein, wherein the particulate matter comprises: a) a polysaccharide in intimate non-covalent association with silica nanoparticles having a hydrophobic surface, wherein the size of the silica nanoparticles is between 1-100 nanometres; and b) a protein or peptide having therapeutic activity, non-covalently associated with said silica nanoparticles and the polysaccharide. Also disclosed is a method of manufacture.