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METHOD FOR DIAGNOSTICS OF MITOCHONDRIA-DEPENDENT REACTIONS OF OXIDATIVE HOMEOSTASIS AT INJURIES OF FACIAL CRANIUM

机译:诊断面颅损伤的线粒体依赖氧化反应的方法

摘要

Method for diagnostics of mitochondria-dependent reactions of oxidative homeostasis at injuries of facial cranium includes measurement of level of content in blood plasma of primary and secondary products of oxidative modification of lip[id, protein components of membranes of cells and determination of content of ferments of anti-oxidation unbalance of metabolic decompensation. Preliminarily in lymphocytes of peripheral blood of patients one determines content of laclatdehydrogenase and level of total carnitine in blood serum before beginning of treatment and repetitively in 2-3 days. When index of histo-chemical activity of lactatdehydrogenase exceeds, and of total carnitine is smaller compared to previous level one makes conclusion on mitochondrial-energy deficient variant of reaction of oxidative homeostasis in patient with traumatic injuries of facial cranium and vice versa.
机译:诊断面部颅骨损伤时线粒体依赖性氧化稳态的反应的方法包括:测定脂质氧化修饰的初级和次级产物血浆中的含量水平,细胞膜的蛋白质成分以及测定发酵物中的含量抗氧化失衡的代谢失代偿。最初,在患者的外周血淋巴细胞中,在开始治疗前以及每隔2-3天,即可确定血清laclatdehydrogenase的含量和血清总肉碱水平。当乳酸脱氢酶的组织化学活性指数超过先前水平,而总肉碱含量低于先前水平时,一个结论就是线粒体能量不足的面部颅骨外伤患者氧化稳态反应的变异,反之亦然。

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