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METHOD FOR THE PRODUCTION OF SYNTHETIC DERIVATIVES OF DIBENZYLBUTYROLACTONE LIGNANES WITH ANTICHAGAS PROPERTIES
METHOD FOR THE PRODUCTION OF SYNTHETIC DERIVATIVES OF DIBENZYLBUTYROLACTONE LIGNANES WITH ANTICHAGAS PROPERTIES
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机译:具有抗霉菌特性的二苄基丁内酯木质素的合成衍生物的生产方法
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摘要
The invention refers to a process to obtain lignans, especially to obtain cubebin and methylpluviatolide from leaves of Zanthoxylum naranjillo or Piper cubeba. It also refers to a process to obtain semi-synthetic derivatives of cubebin, especially dibenzylbutirloactonic lignans, such as: hinokinin, o-acetyl cubebin, o-methyl cubebin, 6,6'-dinitrohinokinine and o-dimethylethylamine cubebin and other derivatives which may be obtained, as well as to obtain methylpluviatolide derivatives, which are used to manufacture drugs to provide activity at least five times higher than observed for gentian violet and other compounds used heretofore for blood treatment and Chagas' disease prophylaxis.
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