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Method and kit for in vitro prognosis or prediction of respuestapor of rheumatoid arthritis patients to treatment with TNFalpha factor blocking agents.

机译:用于类风湿关节炎患者的respuesta por的体外预后或预测用TNFα因子阻断剂治疗的方法和试剂盒。

摘要

Method and kit for in vitro prognosis or prediction of the response from rheumatoid arthritis patients to treatment with TNF blockers factor alpha.; An in vitro method and kit for prognosis or prediction of response to treatment with TNF blocking agents alpha factor from patients with rheumatoid arthritis, comprising determining in a blood sample of said patient the expression level of at least one of the eight genes selected from the group: HLA-DRB3, eat2, GNLY, CAMP, SLC2A3, IL2RB, MXD4 and TLR5 or combinations thereof and comparing said expression level with respect to the expression values ​​obtained from patients treatment responders and nonresponders to it.
机译:类风湿关节炎患者对TNF阻滞因子α治疗的预后或预测的方法和试剂盒。一种用于预测或预测类风湿性关节炎患者对TNF阻断剂α因子治疗反应的体外方法和试剂盒,包括确定所述患者血液样品中至少一种的表达水平从以下八种基因中选择一种:HLA-DRB3,eat2,GNLY,CAMP,SLC2A3,IL2RB,MXD4和TLR5或其组合,并将所述表达水平与从患者治疗应答者和非应答者获得的表达值进行比较它。

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