METHODS OF TREATING PULMONARY DISEASES MEDIATED BY POLYUNSATURATED LIPID METABOLITES AND ASSAYS FOR EPOXIDE HYDROLASE INHIBITORS

摘要

The present invention provides methods of treating inflammatory diseasesmediated by polyunsaturated lipid metabolites by inhibiting epoxide hydrolase,methods for assaying or screening the epoxide hydrolase inhibitors forinhibitory specificity and for toxicity, and novel biologically activetetrahydrofuran diols of arachidonic acid, including antibodies thereto.