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NET, A TRANSCRIPTION FACTOR OF THE TCF FAMILY, AS REGULATOR OF ANGIOGENIC FACTOR EXPRESSION
NET, A TRANSCRIPTION FACTOR OF THE TCF FAMILY, AS REGULATOR OF ANGIOGENIC FACTOR EXPRESSION
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机译:NET,TCF家族的转录因子,作为血管生成因子表达的调节因子
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摘要
The present invention relates to the regulation of the activity of NET(ERP/SAP-2) protein and to compounds which modify or regulate NET proteinactivity. The invention further relates to methods of screening for agonistsor antagonists of NET in order to identify new pro-angiogenic or anti-angiogenic compounds and to therapeutic uses of these compounds. The inventionalso relates to transgenic animals bearing mutations in NET gene.
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