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METHOD FOR ASSAYING NON-SPERMINE/SPERMIDINE ACTIVITY OF SPERMIDINE/SPERMINE N1-ACETYLTRANSFERASE (SSAT)
METHOD FOR ASSAYING NON-SPERMINE/SPERMIDINE ACTIVITY OF SPERMIDINE/SPERMINE N1-ACETYLTRANSFERASE (SSAT)
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机译:精子/精子N1-乙酰转移酶(SSAT)非精子/精子活性的测定方法
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摘要
This invention relates to a method for assaying activity of the enzymespermidine/spermine N1-acetyltransferase (SSAT) using SSAT substrates bydetecting acetylated forms of the SSAT substrates. SSAT substrates may includeamantadine wherein metabolism of amantadine occurs in part by the action ofthe inducible enzyme SSAT to produce the acetylated metabolite N-acetylamantadine.
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