Process for generating sequence-specific proteases by directed evolution and use thereof

摘要

#$%^&*AU2009200749B220110825.pdf#####P:MOPERUDJProposcd AmendeL30739185 div.dec-23/02/2009 ABSTRACT A process for generating sequence-specific proteases by screening-based 5 directed evolution is disclosed. The use of the process provides proteases recognizing and cleaving user-definable amino-acid sequences with high sequence-specificity. Proteases obtainable by the process can be used in a variety of medical, diagnostic and industrial applications.