首页> 外国专利> COMPOSITION FOR SKIN REGENERATION, CONTAINING A SECRETION IN THE CULTURE OF AN EMBRYONIC STEM CELL-DERIVED ENDOTHELIAL PROGENITOR CELL OR FRACTIONS THEREOF, AND USE THEREOF

COMPOSITION FOR SKIN REGENERATION, CONTAINING A SECRETION IN THE CULTURE OF AN EMBRYONIC STEM CELL-DERIVED ENDOTHELIAL PROGENITOR CELL OR FRACTIONS THEREOF, AND USE THEREOF

机译:用于皮肤再生的成分,包含在胚胎干细胞来源的内皮祖细胞或其片段的培养物中分泌的成分,并使用它们

摘要

The present invention relates to a composition for skin regeneration, using a culture medium or a secretion in the culture of an embryonic stem cell-derived endothelial progenitor cell, and to the use thereof. As the present invention uses the secretion in the culture as a medicine and not the embryonic stem cell-derived endothelial progenitor cell itself, the risk of teratoma formation is prevented, and angiogenic activity is promoted to achieve improved effectiveness in healing wounds and burn wounds. The composition of the present invention, when used as a material in cosmetics, increases collagen synthesis and thus prevents skin aging. Particularly, the composition of the present invention in which the secretion in the culture is concentrated into a high concentration provides superior wound-healing effects as compared to a conventional human growth hormone (hGH).
机译:本发明涉及用于皮肤再生的组合物,其使用培养基或来自胚胎干细胞的内皮祖细胞的培养物中的分泌物及其用途。由于本发明使用培养物中的分泌物作为药物而不是胚胎干细胞来源的内皮祖细胞本身,因此可以防止畸胎瘤形成的风险,并且可以促进血管生成活性,从而提高伤口愈合和烧伤创面的有效性。当本发明的组合物用作化妆品中的材料时,可增加胶原蛋白的合成并因此防止皮肤老化。特别地,与常规的人类生长激素(hGH)相比,其中培养物中的分泌物被浓缩成高浓度的本发明的组合物提供了优异的伤口愈合效果。

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