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PROBE FOR DETECTING THE RESISTANCE OF MYCOBACTERIUM TUBERCULOSIS TO DRUGS, AND KIT FOR SAME
PROBE FOR DETECTING THE RESISTANCE OF MYCOBACTERIUM TUBERCULOSIS TO DRUGS, AND KIT FOR SAME
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机译:用于检测结核菌对药物的耐药性和相同试剂盒的探针
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摘要
The present invention relates to a probe for detecting if drugs used as anti-tuberculosis agents are resisted, to a kit for same, and to a detection method thereof, and more particularly, to a primer which can amplify resistance-related genes to the main anti-tuberculosis agents such as rifampin, isoniazid, ofloxacin, kanamycin, and streptomycin, to a probe for detecting if the corresponding gene has resistance-related mutations, and to a kit for detecting the resistance of Mycobacterium tuberculosis to drugs including the primer and the probe. When the kit and method of the present invention are used, a more effective treatment of patients with tuberculosis can be achieved by detecting if Mycobacterium tuberculosis is resistant to the main anti-tuberculosis agents, such as rifampin, isoniazid, ofloxacin, kanamycin, and streptomycin more quickly and accurately than the prior art.
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