A differentially expanded vascular graft (10) for implantation within a body includes a PTFE tube (12) formed of a homogeneous material. The PTFE tube has a longitudinal first portion (14) which has been longitudinally expanded, and a longitudinal second portion (16) which has been longitudinally expanded. The first and second portions have respective microstructures which are different from one another. A method and apparatus for making the differentially expanded vascular graft of the present invention facilitates the formation of the various expanded portions of the PTFE tube. A quality control mechanism includes measuring a characteristic of the microstructure and re-expanding the PTFE tube if characteristic is not sufficiently close to a reference.
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