METHOD FOR PREDICTION OF RISK OF POLYPOIDAL CHOROIDAL VASCULOPATHY

摘要

Disclosed is a method for predicting the risk of polypoidal choroidal vasculopathy, which comprises: a step of detecting in vitro alleles of a single nucleotide polymorphism located at position-17 in at least one nucleotide sequence selected from the group consisting of the nucleotide sequences represented by SEQ ID NO:1 to SEQ ID NO:70 or a complementary sequence thereof, in nucleic acid molecules contained in a sample derived from a subject (a detection step); and a step of determining whether or not at least one of the detected alleles is a risk allele (a determination step). By analyzing an allele or genotype of the single nucleotide polymorphisms in a sample by the method, it becomes possible to determine the presence or absence and/or the severity of the potential risk of polypoidal choroidal vasculopathy in a sample donor.