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METHODS FOR MODULATING A PDGF-AA MEDIATED BIOLOGICAL RESPONSE
METHODS FOR MODULATING A PDGF-AA MEDIATED BIOLOGICAL RESPONSE
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机译:调节PDGF-AA介导的生物反应的方法
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摘要
The present invention is directed towards methods and means for modulating PDGF-AA mediated biological responses and is based, at least in part, on examining the association of various proteins with TMEFF2 and identification of PDGF-AA as a major growth factor that interacts specifically with TMEFF2. The invention provides the first evidence that TMEFF2 can function to regulate PDGF signaling, to help illuiminate the seemingly conflicting biological roles of TMEFF2 in human cancers.
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