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ANTI-Pandemic (H1N1) 2009 ANTIBODY AND IMMUNOASSAY METHOD USING SAME

机译:使用同一抗体的2009年H1N1抗体和免疫分析方法

摘要

Disclosed is a means for detecting porcine-derived human influenza virus type-A pandemic (H1N1) 2009 readily, rapidly and distinctively from other human influenza viruses type-A. Specifically disclosed is an antibody or an antigen-binding fragment thereof, which is produced using a region lying between aa420 to aa434 in the amino acid sequence for pandemic (H1N1) 2009 as an immunogen, wherein the region acts as an epitope and the antibody or the antigen-binding fragment thereof can bind specifically to a core protein of pandemic (H1N1) 2009 through the region. The use of the antibody or the antigen-binding fragment thereof enables the detection of pandemic (H1N1) 2009 in a sample readily and distinctively from other type-A viruses.
机译:公开了一种与其他人类A型流感病毒容易,快速和区别地检测猪源性人类A型流感病毒(H1N1)2009的方法。具体公开了一种抗体或其抗原结合片段,其使用大流行性流感(H1N1)2009氨基酸序列中aa420至aa434之间的区域作为免疫原产生,其中该区域充当表位,并且该抗体或其抗原结合片段可通过该区域特异性结合大流行性流感(H1N1)2009的核心蛋白。抗体或其抗原结合片段的使用使得能够容易且与其他A型病毒区别地检测样品中的大流行(H1N1)2009。

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