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THERAPY OPTIMIZATION FOR CANCER PATIENTS BY TESTING THERAPY COMBINATIONS BY MEANS OF IN VITRO TESTS

机译：通过体外检测方法对治疗组合的检测来优化癌症患者的治疗

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Currently, there is no diagnostic that can evaluate various therapy options for a patient in a test system. In particular, the influences of different nutrient supplies and oxygen supplies (modified by nourishment or medications) on a chemotherapeutic treatment using cytostatic agents cannot yet be diagnostically evaluated. These influences can be evaluated by using a functional test system that observes living tumor cells in vitro. This can be achieved in the functional test systems in particular by reducing or omitting glucose and/or oxygen. Said method can be used in all aspects of oncology. 展开▼

机译：当前，没有诊断能够在测试系统中为患者评估各种治疗选择。尤其是，尚不能从诊断上评估不同营养素供应和氧气供应（通过营养或药物进行修改）对使用细胞抑制剂进行化学疗法的影响。可以使用功能性测试系统评估这些影响，该系统可以在体外观察活体肿瘤细胞。这可以在功能测试系统中特别是通过减少或省略葡萄糖和/或氧气来实现。所述方法可用于肿瘤学的所有方面。展开▼

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公开/公告号WO2011098060A3

专利类型

公开/公告日2011-11-10

原文格式PDF

申请/专利权人 KISCHKEL FRANK CHRISTIAN;
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申请/专利号WO2010DE01532

发明设计人 KISCHKEL FRANK CHRISTIAN;
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申请日2010-12-29

分类号G01N33/50;

国家 WO

入库时间 2022-08-21 17:56:11

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1. 体外检测上皮肿瘤细胞培养物对治疗剂反应性的方法和试剂盒 [P] . 中国专利： CN108018331A . 2018-05-11

2. 一种优化的体外抗过敏作用检测方法 [P] . 中国专利： CN106053450A . 2016-10-26

3. Therapy optimization in the case of cancer patients by testing of therapy combinations by means of in vitro tests (senres - test) [P] . 德国专利： DE102008058984B4 . 2011-09-15

机译：对于癌症患者，通过体外测试（感官测试）来测试治疗组合，从而优化治疗

4. Therapy optimization in the case of cancer patients by testing of therapy combinations by means of in vitro tests (addition) [P] . 德国专利： DE102010007243B4 . 2011-11-17

机译：对于癌症患者，通过体外测试（添加）对治疗组合进行测试来优化治疗

5. THERAPY OPTIMIZATION FOR CANCER PATIENTS BY TESTING THERAPY COMBINATIONS BY MEANS OF IN VITRO TESTS [P] . 世界知识产权组织专利： WO2011098060A2 . 2011-08-18

机译：通过体外检测方法对治疗组合的检测来优化癌症患者的治疗

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3. Patients with distal intestinal gastric cancer have superior outcome with addition of taxanes to combination chemotherapy, while proximal intestinal and diffuse gastric cancers do not: does biology and location predict chemotherapy benefit? [J] . Sedef Ali Murat, Kose Fatih, Sumbul Ahmet Taner, Medical oncology . 2015,第2期

4. An in vitro model for preclinical testing of endocrine therapy combinations for prostate cancer. [J] . Pfeiffer MJ, Mulders PF, Schalken JA The Prostate . 2010,第14期

5. Endometrial carcinoma in vitro chemosensitivity testing of single and combination chemotherapy regimens using the novel microculture kinetic apoptosis assay: implications for endometrial cancer treatment [J] . Ballard Karen S., Homesley Howard D., Hodson Charles, Journal of Gynecologic Oncology . 2010,第1期

6. Weibull regression model for testing factors affecting survival of cancer patients with Electro-Capacitive Cancer Therapy (ECCT) [C] . Hamid Dimyati, Sri Haryatmi International Conference on Applied Statistics . 2014

7. Multicellular tumor spheroid cultures for in vitro testing of focused ultrasound-based combination anticancer therapies. [D] . Ratnayaka, Sithira H. 2013

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