Copper-catalyzed formation of carbon-oxygen bonds

摘要

The present invention provides a method represented by Scheme 1:whereinXrepresents I, Br, Cl, alkylsulfonate, or arylsulfonate;Zrepresents optionally substituted aryl, heteroaryl or alkenyl;catalystcomprises a copper atom or ion, and a ligand;baserepresents a Bronsted base; andRrepresents optionally substituted alkyl, cycloalkyl, aralkyl, heteroaralkyl, alkenylalkyl, or alkynylalkyl.