GENE THERAPY FOR HEMATOPOIETIC TUMOR BY PROLIFERATION-REGULATED VIRUS VECTOR CARRYING SURVIVIN PROMOTER

摘要

Disclosed are: a novel dosage form of a proliferation-regulated virus vector, which enables the gene therapy for hematopoietic tumor using the vector; and a novel therapy means for hematopoietic tumor using the dosage form. Specifically disclosed are: a therapeutic agent for hematopoietic tumor, which comprises a proliferation-regulated virus vector carrying a nucleic acid that encodes at least one protein necessary for the replication of viruses and is under the regulation of a promoter for a gene capable of being expressed specifically in a hematopoietic tumor cell (preferably a survivin gene), and which is characterized by being administered systemically in such a form that a hematopoietic tumor cell is infected by the vector; and others.