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TOR-INTERACTING PROTEINS (TIPS) AND GENES THEREFOR

机译:TOR相互作用蛋白(提示)及其基因

摘要

Broad experimental tools that include biochemical molecular developmental global genomics and loss and gain of function transgenic approaches have been applied to address target of rapamycin (TOR) signaling pathway in plants especially using Arabidopsis model system and Brassica napus crop Towards this objective, putative TOR interacting proteins (TIPs) have been identified and functions of these implicated in diverse developmental and biochemical processes have been investigated Functional studies including over-expression and silencing of TIPs have shown a range of phenotypes that include nutrition-use-efficiency, altered plant architecture and stress resistance in transgenic Arabidopsis and Brassica lines Some of these phenotypes are relevant to important developmental pathways implicated in canola crop yield and performance.
机译:广泛的实验工具,包括生化分子发育的全球基因组学以及功能丧失和获得功能的转基因方法,已被用于解决植物中雷帕霉素(TOR)信号转导途径的目标,特别是使用拟南芥模型系统和甘蓝型油菜作物来实现这一目标时,推定的TOR相互作用蛋白(TIPs)已被鉴定,并研究了它们在多种发育和生化过程中的功能。功能研究包括TIPs的过表达和沉默显示了一系列表型,包括营养利用效率,改变的植物结构和抗逆性在转基因拟南芥和芸苔属品系中,这些表型中的某些与油菜籽作物产量和表现有关的重要发育途径有关。

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