COMPOSITION CONTAINING 5-HT RECEPTOR ANTAGONIST FOR TREATING DIABETIC VASCULAR COMPLICATION

摘要

PURPOSE: A composition containing 5-HT receptor antagonist for treating diabetic vascular complication is provided to suppress Kv channel inhibition and to reduce PKC expression. ;CONSTITUTION: A composition for treating diabetic vascular complication contains an antagonist of 5-HT(5-hydroxytryptamine) receptor as an active ingredient. The 5-HT suppresses Kv channel through PKC activation and is 5-HT2A receptor. The diabetic vascular complication is atherosclerosis, hypertension, angina, or cerebral infarction.;COPYRIGHT KIPO 2011