Pharmaceutical compositions containing chemicals having an inhibition activity on SRC-1 and RTK or pharmaceutically acceptable salts thereof as an active ingredient for the prevention or treatment of angiogenesis-related diseases or cancer

摘要

PURPOSE: A compound having activity of SRC-1 and RTK(Receptor tyrosine kinase) is provided to suppress angiogenesis and signal transduction of cancer cells. CONSTITUTION: A pharmaceutical composition for preventing or treating angiogenesis contains a 7-cyclohexylamino-14H-naphto2,3-a-phenoxazine-8,13-thion of chemical formula 1, 4(4-dimethylamino-2methyl-phenylazo)-benzonitrile or pharmaceutically acceptable salt as active ingredient. The pharmaceutical composition additionally contains a pharmaceutically acceptable carrier. A pharmaceutical composition for preventing or treating cancer contains the compound of chemical formula 1 and 2 or their pharmaceutically acceptable salt as an active ingredient.