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METHODS FOR GENETIC MODIFICATION OF HEMATOPOIETIC PROGENITOR CELLS AND USES OF THE MODIFIED CELLS
METHODS FOR GENETIC MODIFICATION OF HEMATOPOIETIC PROGENITOR CELLS AND USES OF THE MODIFIED CELLS
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机译:造血祖细胞的遗传修饰方法及修饰细胞的用途
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摘要
Described are compositions and methods relating to gene therapy, particularly as applied to hematopoietic progenitor (HP) cells, to transduced cells and methods of obtaining them, and to methods of using them to provide prolonged engraftment of modified hematopoietic cells in human subjects. The invention particularly relates to ex vivo gene therapy of HP cells for treatment or prevention of HIV infection.
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