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Method for detecting target molecule using selective aggregation of quantum dots

机译:利用量子点的选择性聚集检测靶分子的方法

摘要

The present invention relates to a method of detecting a target substance using selective aggregation of quantum dots. According to the present invention, when the target material is present in the quantum dot tagging a fluorescent substance to the target substance or detecting material by using a developer to selectively agglomerated, or the like without the need for pre-treatment of the target material by the reduction in fluorescence of whether or not to process the nanoparticle surface Visually it is possible to easily identify the presence. Therefore a very efficient when using the method of the present invention can be easily and quickly detect a target substance at low cost without the need for special analysis device. In particular, by making sure that you do when using the method of the present invention in the analysis of single nucleotide polymorphisms in the DNA, so that aggregation of quantum dots does not occur, to quickly and efficiently determine the presence of single nucleotide polymorphisms, the diagnosis and treatment of genetic disorders, and biological, can be very useful for use in medical research.
机译:本发明涉及一种使用量子点的选择性聚集来检测目标物质的方法。根据本发明,当目标材料存在于量子点中时,将荧光物质标记到目标物质上或通过使用显影剂选择性地团聚等检测材料而无需通过对目标材料进行预处理。可见是否可以处理纳米颗粒表面的荧光的减少,可以容易地识别其存在。因此,在使用本发明的方法时非常有效的是可以容易且快速地以低成本检测目标物质,而不需要专门的分析装置。特别地,通过确保在使用本发明的方法分析DNA中的单核苷酸多态性时确保不会出现量子点的聚集,从而快速有效地确定单核苷酸多态性的存在,遗传疾病和生物学疾病的诊断和治疗在医学研究中可能非常有用。

著录项

  • 公开/公告号KR101035352B1

    专利类型

  • 公开/公告日2011-05-20

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20090043333

  • 申请日2009-05-19

  • 分类号G01N21/76;C12Q1/68;

  • 国家 KR

  • 入库时间 2022-08-21 17:50:17

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