Androgen receptor corepressor-19kDa as an inhibitor of steroid synthesis in animal reprpductive organ

摘要

The present invention relates to ARR19 (Androgen receptor corepressor-19kDa) for inhibiting steroid synthesis in an animal gonad, and more particularly, an enzyme that inhibits the synthesis of testosterone, a hormone in the gonad of an animal, or is involved in steroid synthesis. It relates to ARR19 for inhibiting steroid synthesis, characterized by inhibiting the protein expression of StAR, 3β-HSD, P450scc, P450c17.;ARR19 for inhibiting steroid synthesis of the present invention can be usefully used in the medical field, etc. in order to prevent and treat diseases caused by the overproduction of animal hormones, through which there is no side effect that can effectively control the hormone to maintain homeostasis in the body It acts as a regulator.;Steroid synthesis, Androgen receptor corepressor-19kDa (ARR19), steroid acute regulatory (StAR), hydroxysteroid dehydrogenase (3β-HSD), P450scc, P450c17