METHOD FOR DIAGNOSIS OF TOBACCO syndrome phenotypically FETUS

摘要

Method phenotypic diagnosis tobacco fetal syndrome consists in the fact that on the basis of the work diagnostic coefficients calculated on the basis of mathematical data processing in accordance with the procedure inhomogeneous sequence statistical Wald procedure when compared phenotypic traits in neonates exposed and not exposed to the toxic effects of nicotine, It can be identified among full-term infants of those who were subjected to the toxic effects of tobacco products th smoke antenatal diagnosis based on the summation of the coefficients of phenotypic traits: saddle nose - 5.4; Index of width to length of the filter head (10,21 ± 4,02) 4,35; short filter - 2.9 less than 1 cm; dysplastic ears - 2.59; sandalevidnaya slot - 2.58; blue sclera - 1.58; low position of the ears - 1.09; long palpebral fissure - more than 2.1 cm, 0.77; broad nasal bridge - 0.41; hypertelorism nipples - 0.43; a filter - a 0.9 cm 0.48; small ears - 0.63; long forearm - more than 8.76 cm, 3.95; age spots - 6.45 and in the diagnosis of fetal tobacco syndrome (a child with intrauterine growth retardation) with 95% probability threshold amount of DC is 13 points, while the total score of -13 to +13 diagnosis is considered uncertain and requires further clarification of information of the mother smoked during pregnancy.